Pretibial Myxomatous Degeneration

Myxomatous degeneration of cardiac valves.

A refmpective study of ten patients with myxomatous degeneration of cardiac valves revealed two patients with "floppy valve syndromen and eight patients with isolated myxomatous change of apparently diverse etiology. The myxomatous degeneration can be seen in a minor degree in normal valves and to a greater extent in clinical and experimental diseases of unknown etiology. The dBicnlties encormt...

Severe pretibial myxedema.

Although pretibial myxedema (PTM) occurs in 4.3% of patients with Graves's disease, the most severe variant, elephantiasis nostras verrucosa, is found in less than 1% of cases. The most frequent location of infiltration is the lower extremities, especially the pretibial areas and on the dorsum of the foot. The authors report one of the most severe cases of elephantiasis nostras verrucosa, follo...

Differentiating the aging of the mitral valve from human and canine myxomatous degeneration.

During the course of both canine and human aging, the mitral valve remodels in generally predictable ways. The connection between these aging changes and the morbidity and mortality that accompany pathologic conditions has not been made clear. By exploring work that has investigated the specific valvular changes in both age and disease, with respect to the cells and the extracellular matrix fou...

Case of Myxomatous Degeneration of the Chorion; Profuse Hæmorrhage; Transfusion; Recovery

Sildenafil improves heart rate variability in dogs with asymptomatic myxomatous mitral valve degeneration

Myxomatous mitral valve degeneration (MMVD) causes an imbalance of sympathovagal activity resulted in poor cardiac outcomes. Phosphodiesterase-5 inhibitors have been revealed cardioprotective effect in patients with heart diseases. This study aimed to 1) compare the heart rate variability (HRV) between asymptomatic MMVD and healthy dogs and 2) assess long-term effects of sildenafil and enalapri...